1. SHEDDING: DEFENSE AGAINST URINARY SHEDDING CAUSED BY 4 KEY LEPTOSPIRA SEROVARS
PREVENT URINARY SHEDDING OF LEPTOSPIRES22
A key objective of vaccination is to shown to be effective against urinary shedding of leptospires, which has potential zoonotic risk:22,23
- 0% of dogs vaccinated with Nobivac® Canine 1-DAPPv+L4 developed leptospiruria
- All of the control dogs challenged with L. canicola and L. grippotyphosa, 80% of control dogs challenged with L. icterohaemorrhagiae, and 50% of control dogs challenged with L. pomona developed leptospiruria
Nobivac® Lepto4 is shown to be effective against leptospiruria associated with
- L. prippotyphosa
- L. canicola
- L. icterohaemorrhagiae
- L. pomona